Univariate analysis revealed that the p16/HPV status, tumor stage per the 8th edition AJCC system, and ERα and p53 expression are associated with both progression-free survival (PFS) (p < 0.001, p = 0.004, p = 0.044, and p = 0.001, respectively) and OS (p < 0.001, p < 0.001, p = 0.002, and p = 0.002, respectively). This evidence concerns the gene ESR1 and neoplasm.