IGF1R and diffuse large B-cell lymphoma: To further verify whether IGF-1R alters YAP activity by regulating the Hippo-YAP signaling pathway, we examined the effects of IGF-1R inhibitors on the subcellular expression of YAP in DLBCL cells by separating the nuclear and cytoplasmic proteins in DLBCL cells and detecting the subcellular expression of YAP protein.