ITGAM and neuroblastoma: The expression of CD11b, a marker of microglial activation, was upregulated in cerebral cortical microglias incubated with sera from children with OMS and NB (3.41 ± 0.32 ng/mg total protein OMS + NB, 0.99 ± 0.09 ng/mg total protein NB, 1.09 ± 0.12 ng/mg total protein healthy control, p < 0.001 vs NB, p < 0.001 vs healthy control), whereas CD11b concentration was not statistically changed by sera of children with only NB at least under our experimental conditions (Fig. 1a).