Central obesity was associated with increased Klotho levels [156.4 pg/ml vs 118.5 pg/ml, p = 0.0275] and FGF21 levels [93.0 pg/ml vs 70.1 pg/ml, p = 0.0193] as well as a decrease in FGF19 levels [160.6 pg/ml vs 229.4 pg/ml, p = 0.0264] (Table 3). The gene discussed is FGF19; the disease is Abdominal obesity.