Among patients without 11p15 LOM or upd(7)mat, other imprinting disturbances such as Temple syndrome, maternal uniparental disomy of chromosome 16 (upd(16)mat), maternal uniparental disomy of chromosome 20, pathogenic copy number variations (PCNVs), and mutations in IGF2 on the paternal allele and CDKN1C on the maternal allele, which are causative genes for SRS, were identified in some cases [1]. The gene discussed is IGF2; the disease is Silver-Russell syndrome.