Finally, pro-inflammatory cytokines, in particular, IL-1β, IL-6, and TNFα, which are elevated in patients with COVID-19 induce the loss of the normal antithrombotic and anti-inflammatory functions of endothelial cells, leading to coagulation dysregulation, complement and platelet activation, and leukocyte recruitment in the microvasculature [17]. The gene discussed is IL6; the disease is COVID-19.