Metastasizing ovarian cancer cells can activate p38α MAPK signaling in omental CAFs, and CAF-derived p38α MAPK-regulated cytokines and chemokines, including IL-6, CCL5, and CXCL10, induce glycogen metabolism in cancer cells via glycolysis, which mediates energy production and promotes the aggressiveness of ovarian cancer cells [58]. The gene discussed is CCL5; the disease is ovarian cancer.