In Model 1, adjusting for age, gender, education, hypertension and albumin, SPF was significantly associated with poor physical performance measured by SPPB (odds ratio, OR = 7.66, 95% confidence interval, CI = 1.43–41.14) and low physical activity (OR = 3.66, 95% CI = 1.67–8.02), whereas SF was significantly associated with low mood (OR = 6.88, 95% CI = 1.23–38.66); malnutrition risk (OR = 11.13, 95% CI = 1.91–64.97); poor physical performance (OR = 17.51, 95% CI = 2.63–116.58); and low physical activity (OR = 4.46, 95% CI = 1.37–14.54). The gene discussed is ALB; the disease is nutritional deficiency disease.