TF and Stroke: Furthermore, TF decreased the expression of the pro-inflammatory cytokines CXCL10, CCL2 and IL-6 in human microglia–monocyte co-cultures stimulated with HIV particles [146], and lower levels of the pro-inflammatory proteins IL-1β, COX2 and 3-NT were detected following the TF treatment of mice with tMCAO-induced stroke [254].