A difference was found between male mice with and without primary tumor differed in IL-10 and IL-16 levels, which were higher in those with tumor, and in CXCL5, CXCL11, CXCL13, CXCL16, and CCL24 levels, which were higher in those without tumor (Figure 4B). This evidence concerns the gene CXCL13 and neoplasm.