Numerous published studies also reported that Cur, and its analogs, initiated cancer cell cycle arrest in both G1 and G2/M phases, depending on the type of cancer [21,22,23].Taken together, these findings suggest that DZG and Cur suppressed PLS10 cells proliferation via the inhibition of cyclin D1 expression, leading to cell cycle arrest in the G1 phase. This evidence concerns the gene CCND1 and cancer.