MAPT and Alzheimer disease: Tau protein has been extensively studied in the context of several neurodegenerative disorders, including AD [102,103], frontotemporal dementia (FTD) [104,105], and related tauopathies, including progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), Down’s syndrome (DS), PD, and dementia with Lewy bodies (DLB) [106].