Following an additional 12 weeks of the HF/S diet, PGC1a, CS and TNFα expression was significantly higher in the CON group compared to the OBC group (p < 0.01, Figure 5E,I,O), whereas MAFbx and MURF1 expression was significantly lower in the CON group compared to the OBC group in males (p < 0.01, Figure 5S,U). The gene discussed is PPARGC1A; the disease is hydrops fetalis.