Despite the absence of relevant differences in lipids and insulin levels, PCOS patients compared to the control group were characterized with a higher visceral adiposity index (VAI) (1.0 (0.6–1.6) vs. 0.7 (0.5–1.0), p = 0.0461), which indicates an increased risk of cardio-metabolic disorders in patients with PCOS already in adolescence (Table 1). The gene discussed is INS; the disease is polycystic ovary syndrome.