Regarding the phosphorylation of mTOR, Akt, and AMPK in H. pylori-stimulated gastric tissues and cells, Xie et al. [79] studied the correlation between H. pylori infection and activation of the phosphatidylinositol-3-kinase/Akt (PI3K/Akt) pathway in the mucosal tissues of the patients with chronic atrophic gastritis and gastric cancer. Here, AKT1 is linked to gastric cancer.