FASN and metabolic dysfunction-associated steatotic liver disease: Additionally, it was described by Iliopoulos et al. [29] that miR-122 overexpression in HepG2 cells also resulted in increased SREB-1c expression along with the aforementioned ACC-1 and FASN. The culminating evidence indicated a critical role of miR-122 in hepatic de novo lipogenesis regulation and, in consequence, NAFLD development, a common condition among patients affected by either MetS or T2D.