CDH1 and neoplasm: It is speculated that the decreased β-catenin levels in A549shHTATIP tumor tissue homogenates is in part attributable to the decreased membranous and cytoplasmic β-catenin levels associated with the liberation of β-catenin from the cytoplasmic tail of E-cadherin [68] followed by the nuclear translocation of β-catenin that potentially facilitates the transcriptional changes associated with tumor metastasis [69,70].