TTP has been shown to directly regulate EMT regulators, including ZEB1 (zinc finger E-box binding homeobox 1), SOX9 (sex-determining region Y box 9), and MACC1 (metastasis associated in colon cancer 1), all of which are known to be downregulated in colorectal carcinomas (CRC). The gene discussed is ZFP36; the disease is colorectal carcinoma.