Counts of WBC (AUC = 0.89 at D-1), reticulocytes (AUC = 0.77 at D-1), and platelets (AUC = 0.88 at D+1), TT (AUC = 0.85 at D0), and plasma concentrations of AST (AUC = 0.82 at D0), ALT (AUC = 0.86 at D-2), vWF (AUC = 0.77 at D-1), fibrinogen (AUC = 0.75 at D0), TAT (AUC = 0.75 at D-1) and D-dimer (AUC = 0.80 at D-2) appeared as the best candidate biomarkers to differentiate between dengue and OFI. This evidence concerns the gene VWF and dengue disease.