In different studies, MSC‐derived exosomes carrying miR‐133b, miR‐375, or miR‐584‐5p from transfected MSCs, repressed GBM cell proliferation, invasion, and migration in vitro and in vivo, through the downregulation of EZH2 and the Wnt/β‐catenin signaling pathway.167, 168, 169. Here, EZH2 is linked to glioblastoma.