PDK4 and Duchenne muscular dystrophy: Genes thought to be associated with DCM are dystrophin (DMD) in German Shorthaired Pointers, striatin (STRN) in Boxers, and both pyruvate dehydrogenase kinase 4 (PDK4) and a locus on chromosome 5 in Doberman Pinschers (Sammarco, 2008).