Since at least the P3HR1 “2” tumor tissue used for RNAseq analysis contains cells with both LMP1-high/EBNA-LP-low expression, as well as cells with LMP1-low/EBNA-LP-high expression, the finding that the tumor is monoclonal suggests that cells with each of the two different forms of viral latency were originally derived from the same EBV-infected cell. The gene discussed is PDLIM7; the disease is neoplasm.