Since cells with type II and type I EBV latency use a distinct EBV promoter (Qp) to drive EBNA1 transcription (in contrast to the Cp and Wp promoters used in type III and Wp-restricted latency, respectively), we next performed RT-PCR on RNA isolated from P3HR1 infected tumor tissue versus B95.8 virus infected tumor tissue using PCR primers previously shown to specifically detect EBNA1 transcripts derived from the Qp [49]. This evidence concerns the gene CP and neoplasm.