Neutralization of IL-17 reduced the inflammatory profile in the course of infection, as assessed by histopathological analysis (Fig 3A–3C) when compared to IC group treatment control (S6A Fig), whereas neutralization with anti-IFN-γ slightly intensified the inflammation at day 14, as assessed by histopathological analysis without being reflected in footpad swelling (Fig 3A, 3E and 3F). The gene discussed is IL17A; the disease is infection.