Histopathologically, the number of Ki-67-positive tumour cells in both primary and distant tumours was significantly lower, and the number of not only CD11c + and OX-62+ DCs but CD4+ and CD8+ T cells in both primary and distant tumours was significantly higher after RFA in combination with intratumoural OK-432 injection. The gene discussed is MKI67; the disease is neoplasm.