To test whether p-PDGFR-β overexpression is observed in hepatic tissue of human patients with chronic liver disease, 161 liver samples including 10 samples with viral hepatitis-inflammation, 62 cirrhotic liver samples and 54 hepatocellular carcinoma tissue samples (HBV-positive) were analyzed using immunohistochemistry in this study (Figs. 4 and 5). The gene discussed is PDGFRB; the disease is animal viral hepatitis.