The results revealed that eight patients (Positive rate = 0.80, 8/10) with viral hepatitis-inflammation and 50 patients (Positive rate = 0.81, 50/62) with cirrhosis showed excessive expression level of p-PDGFR-β in the liver fibrotic areas (Supplementary Fig. 2B), while 21 patients (Positive rate = 0.39, 21/54) with hepatocellular carcinoma showed high expression of p-PDGFR-β in their liver samples (Supplementary Fig. 2B), whereas the hepatic tissue samples in normal controls (n = 35) barely expressed visible p-PDGFR-β (Supplementary Fig. 2B). Here, PDGFRB is linked to Cirrhosis.