RIGI and infection: Next, to investigate the role of ANXA1 and RIG-I in IAV-induced cell death, A549, A549∆ANXA1, and A549 ∆RIG-I cells were infected with 1 multiplicity of infection (MOI, i.e., 1 viral particle per cell) H1N1 PR8 virus for 24 and 48 h.