Moreover, in DCIS, p63 marked the myoepithelial cell layer, while in IBC the majority of infiltrating cells became p63-positive, accompanied by a concomitant increase in α-SMA-positive fibroblasts in the stroma associated with IBC, as previously reported (Fig. 9b, c)36. The gene discussed is ACTA1; the disease is ductal breast carcinoma in situ.