Scl:Cdx2 #252 showed a clonal expansion of c-Kit+B220intCD3int cells (Supplementary Fig. 2e), Scl:Cdx2 #882 PB leukemic cells were c-Kit+CD3+mCherry+, representative of acute T-cell leukemia (Supplementary Fig. 2f), but most mice (#2259, #2261, and #472) developed acute myeloid/erythro-myeloid leukemia with a c-Kit+mCherry+ population predominately Gr1+CD11b− (Supplementary Fig. 2g). This evidence concerns the gene ITGAM and T-cell acute lymphoblastic leukemia.