Notably, of the entire series of 185 samples, 121 (65%) CRC demonstrated a high TRF2 expression (TRF2H, score 2+/3+), while high expression of VEGF-A (VEGF-AH, score 2+/3+) was observed in 71 (39%) patients (Fig. 2c and Supplementary Table S3). Here, TERF2 is linked to colorectal carcinoma.