Only CTHRC1 and LPAR5 (Fig. 1b) were upregulated and MAGI1 (Fig. 1c) was downregulated in lung adenocarcinoma, thyroid carcinoma, and kidney and renal papillary cell carcinoma in addition to invasive breast cancer when these genes were queried from TCGA database. The gene discussed is CTHRC1; the disease is invasive breast carcinoma.