There were no significant associations with disease status or secondary autoimmunity and Teff:Treg ratios, Treg function, Th1 and Th17 cells, CD3 + CD4+ and CD3 + CD8 + CXCR3+ and CCR5+ cells, naïve and memory CD4+ T cell subsets, total B cells, and total memory B cells (supplementary Figure S5). The gene discussed is CXCR3; the disease is Autoimmunity.