SNHG4 and osteosarcoma: For the determination of roles of SNHG4 in osteosarcoma tissues, qRT‐PCR analysis was first conducted to measure the features of SNHG4 expression in 24 osteosarcoma tissues and 24 para‐carcinoma tissues, and revealed considerable upregulation of SNHG4 expression in osteosarcoma tissues (Figure 1a).