Chen et al. found that miR-331-3p is an up-regulated micoRNA in pancreatic cancer (PC), while miR-331-3p inhibits suppression of tumorigenicity 7 like (ST7L) and epithelial mesenchymal transition (EMT)-mediated tumor metastasis, thereby promoting PC cell proliferation. The gene discussed is ST7L; the disease is pachyonychia congenita.