The result of GO and KEGG analysis proved that the OGEs mainly associated with regulation of cell proliferation, differentiation, migration, apoptotic process, negative regulation of cell cycle and found that these OGEs are mainly concentrated upon pancreatic cancer, focal adhesion, PI3K-Akt signaling pathway, which suggests a potential mechanism for PDAC proliferation and metastasis. This evidence concerns the gene AKT1 and pancreatic neoplasm.