Previous studies have revealed that the levels of TLR2 and NF-κB are upregulated in OM (Yoshimura et al., 1999; Dziarski et al., 2001; Kielian et al., 2005) and promote the recruitment of neutrophils to combat pathogens in OM (Krysko et al., 2011; Arroyo et al., 2013). Here, NFKB1 is linked to ocular melanoma.