FLT3 and acute myeloid leukemia: As the optimal approach to using currently available FLT3 inhibitors in AML remains to be defined, one potential strategy consists of using the multi-targeted FLT3 inhibitor midostaurin during induction for debulking and adding the more selective FLT3 inhibitor gilteritinib during consolidation with the goal to further reduce and/or eliminate MRD burden.