Further, LeBlanc et al. (92) injected salmon at 13°C with ISAV and observed that the expression of mx and stat1 only started to be up-regulated at 10 and 20 DPI, respectively, and Caruffo et al. (93) reported that ISAV infection (IP) only induced the transcription of mx in the head-kidney of salmon after 40 DPI. This evidence concerns the gene MX1 and infection.