MMP1 and tuberculosis: Kumar et al. have shown that circulatory levels of MMP-1, -2, -3, -8, and -13 in these patients decrease following successful TB treatment and that MMP-1 (in sputum) and MMP-1, -2, -3, -9, and -12 levels (in serum) were higher in patients with more severe structural lung damage at baseline (47) as determined from chest x-rays.