ASGR1 and cyclic hematopoiesis: In another related study, healthy woodchucks which were first immunized with a WcASGPR-closely compatible rabbit ASGPR (RbASGPR) and then infected with WHV advanced at a higher frequency to CH, while animals with ongoing CH challenged with RbASGPR demonstrated exacerbated histological degree of liver injury when compared to the unchallenged animals with CH (143).