MPO and cardiovascular disorder: Excessive production of hypohalous acids has been shown to be directly linked to many cardiovascular diseases (Zhang R. et al., 2001; Anatoliotakis et al., 2013; Ndrepepa, 2019) and circulating levels of MPO is clinically used as a biomarker to predict the health outcomes in those patients (Baldus et al., 2003; Brennan et al., 2003; Meuwese et al., 2007; Mocatta et al., 2007; Schindhelm et al., 2009).