For CRC patients, PTPN3, PTPN7, PTPN11, PTPN12, PTPN13 and PTPN14 were upregulated while PTPN2, PTPN18, PTPN21, and PTPN22 expressions were downregulated according to Oncomine. Here, PTPN22 is linked to colorectal carcinoma.