The result revealed that UBE2I expression was statistically positively linked to PIAS1 (Fig. 7b), NSMCE2 (Fig. 7c), SAE1 (Fig. 7d), RANBP2 (Fig. 7e), UBA2 (Fig. 7f), PIAS4 (Fig. 7g), RANGAP1 (Fig. 7h), SUMO3 (Fig. 7i), SUMO1 (Fig. 7j) or SUMO2 (Fig. 7k) expression in HCC. This evidence concerns the gene SAE1 and hepatocellular carcinoma.