The top five significantly enriched KEGG pathways were MicroRNAs in cancer (hsa05206, FDR = 4.32E−26), Pathway in cancer (hsa05200, FDR = 6.77E−18), PI3K-AKT signaling pathway (hsa04151, FDR = 9.95E−16), Endocrine resistance (hsa01522, FDR = 9.95E−16), and Foxo signaling pathway (hsa04068, FDR = 2.65E−15) (Fig. 3c). This evidence concerns the gene AKT1 and cancer.