Pearson correlation analysis showed that EGFR (R = 0.16, P = 0.00072), PTEN (R = 0.098, P = 0.043), SIRT1 (R = 0.094, P = 0.013), RELA (R = 0.18, P = 0.00013) and CREB1 (R = 0.16, P = 0.00094) were significantly correlated with LDHAP5 expression in ovarian serous cystadenocarcinoma (Table 3). The gene discussed is CREB1; the disease is ovarian serous cystadenocarcinoma.