VEGFA and neoplasm: Consistent with this, patients treated with the monoclonal VEGFA inhibitor bevacizumab or with small molecule PTK787 and SU6668 VEGFR tyrosine kinase inhibitors, exhibit improved tumour blood flow, reduced tumour microvascular density, volume and tumour interstitial pressure but do not exhibit decreased radioactive tracer uptake, indicating improved drug-uptake potential.