MST1R and prostate carcinoma: RON exhibits hypoxia-induced oncogenic alternative splicing in breast, lung, liver, kidney, bladder, ovarian, colon, pancreatic, gastric and prostate carcinomas and many cancer cell lines and is composed of heterodimers of an extracellular 40kda α chain and 150 kDa β chain that contains extracellular, transmembrane and intracellular tyrosine kinase domains, derived from the same immature pre-protein.