MYC and cancer: The Quinilone derivative 1-(4-methoxyphenyl)-3_(4-morpholino-6-nitroquinolin-2-yl)prop-2-en-1-one (compound 25) binds hnRNP K at micromolar concentrations, down-regulates c-Myc transcription and inhibits human cancer cell proliferation and human xenograft tumour growth in mice [315].