CD47 and neoplasm: In cervical tumour cells, the UPR also induces oncogenic activation of the atypical splicing factor SRSF10, resulting in IL1-RAP alternative exon 13 inclusion, membrane associated mIL1-RAP expression and IL1β/IL1R1/mIL1RAP-dependent expression of CD47, the “don’t eat me” inhibitor of macrophage phagocytosis, identifying a UPR/SRSF10/mIL1RAP/CD47-dependent tumour-promoting axis (Fig. 4a )[237].