MGAT3 and Alzheimer disease: The expression of β-1,4-mannosyl-glycoprotein 4-β-N-acetylglucosaminyl transferase (MGAT3) was decreased in PBMCs in patients with AD, whereas the opposite was observed in control patients exposed to Aβ.36 Using MGAT3, small interfering RNA to silence MGAT3 expression inhibited the uptake of Aβ to PBMCs isolated from healthy patients and inhibited monocyte clustering around Aβ, suggesting that MGAT3 may be important in the uptake and degradation of Aβ.36