However, when we further adjust the tumor stage/grade/status of the patients, only LIHC and MESO showed significant survival association with ESR1 mRNA expression (Table S2), while BRCA, KICH, KIRP, LGG, and PAAD patients survival significant association with ESR2 mRNA expression (Table S3). This evidence concerns the gene ESR1 and pancreatic adenocarcinoma.