To further dissect the association of WDFY3‐AS2 expression with ESCC development and progression, GraphPad software was used to investigate the correlations of WDFY3‐AS2 expression with clinicopathological features such as gender, age, smoking, alcohol, tumour differentiation, invasion depth, TNM stage and lymph node metastasis. Here, WDFY3 is linked to esophageal squamous cell carcinoma.