INS and type 2 diabetes mellitus: The present study therefore evaluates the comparative cardiovascular effects of GLP-1ra in comparisons with dipeptidyl peptidase-4 inhibitor (DPP-4i), sulfonylurea (SU), and insulin using the prevalent new-user cohort design [29] to include a broad spectrum of real-world adults with T2D being treated with GLP-1ra to enhance the generalizability of study findings.