MatureLAMP3+ DCs were observed in both HCC and lymph nodes, and these cells werepredicted to interact with T and natural killer cells via IL-15 and PD-1/PD-L1 and,importantly, they were strongly associated with T cell dysfunction.15 Macrophages in HCC were found to occupy 2 distinct states. Here, CD274 is linked to hepatocellular carcinoma.