AD is a progressive neuroinflammatory and neurodegenerative disease of the brain,1 defined by the accumulation and deposition of beta‐amyloid, which has recently been identified as an antimicrobial peptide,2, 3 and the presence of neurofibrillary tangles composed of aggregates of aberrantly phosphorylated tau proteins. The gene discussed is MAPT; the disease is Alzheimer disease.